Abcam/重组人CD3蛋白（活性）（ab220577）/活性（ab220577）
商品编号：
Active)(ab220577
品牌：
Abcam
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description
Product name
Recombinant human CD3 protein (Active)See all CD3 proteins and peptidesBiological activity
Measured by its binding ability in a functional ELISA. Immobilized OKT3 MAb at 10μg/mL (100μL/well) can bind ab220577with a linear range of 0.3-5μg/mL.
Purity
>95% SDS-PAGE.Endotoxin level
<>Expression system
HEK 293 cellsAccession
P07766P09693Protein length
Protein fragmentAnimal free
NoNature
RecombinantAmino Acid Sequence 1
Species
HumanSequence
DGNEEMGGITQTPYKVSISGTTVILTCPQYPGSEILWQHNDKNIGGDEDD KNIGSDEDHLSLKEFSELEQSGYYVCYPRGSKPEDANFYLYLRARVCENC MEMDPredicted molecular weight
39 kDa including tagsAmino acids
23 to 126Tags
His tag C-Terminus,Fc tag C-TerminusAdditional sequence information
Extracellular domain (NP_000724.1).
Amino Acid Sequence 2
Species
HumanSequence
QSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKW NLGSNAKDPRGMYQCKGSQNKSKPLQVYYRMCQNCIELNAATISPredicted molecular weight
39 kDa including tagsAmino acids
23 to 116Tags
DDDDK tag C-Terminus,Fc tag C-TerminusAdditional sequence information
Extracellular domain (AAI13831).
Associated products
Related Products
- Anti-DDDDK tag (Binds to FLAG® tag sequence) antibody (ab1162)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-DDDDK tag (Binds to FLAG® tag sequence) antibody (ab21536)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-6X His tag® antibody (ab9108)
Specifications
Our Abpromise guarantee covers the use ofab220577in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Applications
Functional Studies
SDS-PAGE
Form
Lyophilized
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40Constituents: 5% Trehalose, PBSLyophilized from 0.22 µm filtered solution.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- ReconstitutionReconstitute with sterile deionized water to a concentration of 200 µg/ml.
General Info
Alternative names
- 4930549J05Rik
- A430104F18Rik
- AW552088
see allFunction
The CD3 complex mediates signal transduction.Involvement in disease
Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.Sequence similarities
Contains 1 ITAM domain.Cellular localization
Membrane.- Information by UniProt
品牌介绍
Abcam超过1800种高质量的纯化二抗已在多种应用中得到验证，如蛋白质印迹，免疫组织化学，免疫细胞化学，ELISA和流式细胞仪。了解Abcam如何支持您的研究。
