Overview
Product name
SR95531 (Gabazine), GABAA antagonistDescription
GABAA antagonistAlternative names
- Gabazine
Biological description
Selective, competitive GABAA receptor antagonist. Allosteric inhibitor of channel opening of the GABAA receptor. Displaces [3H]-GABA from rat brain membranes with a Ki of 150 nM.Also available in simple stock solutions (ab144487) - add 1 ml of water to get an exact, ready-to-use concentration.
Purity
>98%CAS Number
104104-50-9Chemical structure
Properties
Chemical name
2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromideMolecular weight
368.23Molecular formula
C15H17N3O3.HBrPubChem identifier
107895Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.Solubility overview
Soluble in water to 25 mMHandling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES
[Br-].COc1ccc(cc1)C=2C=CC(=[NH2+])N(CCCC(=O)O)N=2Source
Synthetic
Research areas
- Neuroscience
- Neurotransmitter
- Amino Acids
- GABA
- Neuroscience
- Neurotransmission
- Receptors / Channels
- Ligand-Gated Ion Channels
- GABA Receptors
- Biochemicals
- Product Range
- Just Add Water
- Biochemicals
- Chemical Type
- Biochemicals
- Biochemicals
- Pharmacology
- Receptors & Transporters
- GABA
- GABAA
- Biochemicals
- Pharmacology
- Receptors & Transporters
- GABA
- GABAA
- Antagonists
- Biochemicals
- Research Area
- Pain & inflammation
- GABA
- GABAA
- Biochemicals
- Research Area
- Pain & inflammation
- GABA
- GABAA
- Antagonists
- Biochemicals
- Research Area
- Schizophrenia
- GABA
- GABAA
- Biochemicals
- Research Area
- Schizophrenia
- GABA
- GABAA
- Antagonists
- Biochemicals
- Research Area
- Stress / Anxiety
- GABA
- GABAA
- Biochemicals
- Research Area
- Stress / Anxiety
- GABA
- GABAA
- Antagonists
