Abcam/Thapsigargin，Ca2+/sup>-ATPase抑制剂（ab120286）/1/ab120286
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3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview
Product name
Thapsigargin, Ca2+-ATPase inhibitorDescription
Ca2+-ATPase inhibitorBiological description
A potent, cell-permeable Ca2+-ATPase inhibitor. Releases Ca2+ by inhibiting endoplasmic reticular Ca2+-ATPase (IC50 = 4-13 nM). Both tumorogenic and apoptotic actions reported.
Purity
>98%CAS Number
67526-95-8Chemical structure
Properties
Chemical name
(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoateMolecular weight
650.76Molecular formula
C34H50O12PubChem identifier
446378Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.Solubility overview
Soluble in DMSO to 100 mMHandling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES
CC=C(C)C(=O)O[C@@H]3[C@@H](OC(=O)CCCCCCC)[C@H]1C([C@@H]2OC(=O)[C@](O)(C)[C@@]2(O)[C@H](C[C@]1(C)OC(C)=O)OC(=O)CCC)=C3CSource
Thapsia garganica
Research areas
- Tags & Cell Markers
- Subcellular Markers
- Organelles
- ER
- Signal Transduction
- Signaling Pathway
- Calcium Signaling
- Calcium Channels
- Signal Transduction
- Metabolism
- Plasma Membrane
- ATPases
- Neuroscience
- Neurotransmitter
- Transporters
- Other Transporters
- Cardiovascular
- Atherosclerosis
- Hypertension
- Sodium/ion transport
- Biochemicals
- Chemical Type
- Biochemicals
- Biochemicals
- Pharmacology
- Enzymes
- ATPase & GTPase
- Inhibitors
- Biochemicals
- Pharmacology
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Pharmacology
- Receptors & Transporters
- Transporters
- Ion pumps / transporter
- Ca2+-ATPase
- Inhibitors
- Biochemicals
- Research Area
- Heart disease
- Calcium
- Metabolism
- Types of disease
- Heart disease
- Biochemicals
- Research Area
- Heart disease
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Pain & inflammation
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Alzheimer"s Disease
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Diabetes
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Heart disease
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Hypertension
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Obesity
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Obesity
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Pain & inflammation
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Respiratory disease
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Respiratory disease
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Stroke
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Stroke
- Signaling
- Ca2+ signaling
- Ca2+-ATPase
- Biochemicals
- Research Area
- Cancer
- Ca2+ signaling
- Ca2+-ATPase
品牌介绍
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