商品介绍
Description
Product name
Recombinant human Hsp70 proteinSee all Hsp70 proteins and peptidesBiological activity
ab78427 has ATPase activity at the time of manufacture of 3.3µM phosphate liberated/hr/µg protein in a 200µl reaction at 37°C (pH7.5) in thepresence of 20ul of 1mM ATP using a Malachite Green assay.Purity
>90% SDS-PAGE.ab78427 is affinity purified.Expression system
Escherichia coliAccession
NM_005345Protein length
Full length proteinAnimal free
NoNature
RecombinantSpecies
HumanSequence
MAKAAAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA LNPQNTVFDA KRLIGRKFGD PVVQSDMKHW PFQVINDGDK PKVQVSYKGE TKAFYPEEIS SMVLTKMKEI AEAYLGYPVT NAVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA IAYGLDRTGK GERNVLIFDL GGGTFDVSIL TIDDGIFEVK ATAGDTHLGG EDFDNRLVNH FVEEFKRKHK KDISQNKRAV RRLRTACERA KRTLSSSTQA SLEIDSLFEG IDFYTSITRA RFEELCSDLF RSTLEPVEKA LRDAKLDKAQ IHDLVLVGGS TRIPKVQKLL QDFFNGRDLN KSINPDEAVA YGAAVQAAIL MGDKSENVQD LLLLDVAPLS LGLETAGGVM TALIKRNSTI PTKQTQIFTT YSDNQPGVLI QVYEGERAMT KDNNLLGRFE LSGIPPAPRG VPQIEVTFDI DANGILNVTA TDKSTGKANK ITITNDKGRL SKEEIERMVQ EAEKYKAEDE VQRERVSAKN ALESYAFNMK SAVEDEGLKG KISEADKKKV LDKCQEVISW LDANTLAEKD EFEHKRKELE QVCNPIISGL YQGAGGPGPG GFGAQGPKGG SGSGPTIEEV DTags
His tag N-Terminus
Associated products
Related Products
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-Hsp70 antibody [5A5] (ab2787)
- Anti-Hsp70 antibody (ab31010)
- Anti-Hsp70 antibody [EP1007Y] (ab45133)
- Anti-Hsp70 antibody [C92F3A-5] (ab47455)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-Hsp70 antibody [3A3] (ab5439)
- Anti-Hsp70 antibody [2A4] (ab5442)
Specifications
Our Abpromise guarantee covers the use ofab78427in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Applications
Functional Studies
Other
Western blot
ELISA
SDS-PAGE
Form
Liquid
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
pH: 7.50Preservative: 1.36% ImidazoleConstituents: 0.87% Sodium chloride, 10% Glycerol, 0.328% Sodium phosphate
This product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
Alternative names
- DnaK type molecular chaperone HSP70 1
- Epididymis secretory protein Li 103
- FLJ54303
see allRelevance
Function: In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.Tissue specificity: HSPA1B is testis-specific.Cellular localization
Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
品牌介绍
Abcam超过1800种高质量的纯化二抗已在多种应用中得到验证，如蛋白质印迹，免疫组织化学，免疫细胞化学，ELISA和流式细胞仪。了解Abcam如何支持您的研究。
