Abcam/重组人GRP78 BiP蛋白（活性）（ab78432）/ab78432
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联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description
Product name
Recombinant human GRP78 BiP protein (Active)See all GRP78 BiP proteins and peptidesBiological activity
ab78432 has ATPase activity at the time of manufacture of 2.3µM phosphate liberated/hr/µg protein in a 200µl reaction at 37°C (pH7.5) in the presence of 20ul of 1mM ATP, using a Malachite Green assay.
Purity
>90% SDS-PAGE.Ab78432 is purified by affinity purification.Expression system
Escherichia coliAccession
P11021Protein length
Full length proteinAnimal free
NoNature
RecombinantSpecies
HumanSequence
MKLSLVAAML LLLSAARAEE EDKKEDVGTV VGIDLGTTYS CVGVFKNGRV EIIANDQGNR ITPSYVAFTP EGERLIGDAA KNQLTSNPEN TVFDAKRLIG RTWNDPSVQQ DIKFLPFKVV EKKTKPYIQV DIGGGQTKTF APEEISAMVL TKMKETAEAY LGKKVTHAVV TVPAYFNDAQ RQATKDAGTI AGLNVMRIIN EPTAAAIAYG LDKREGEKNI LVFDLGGGTF DVSLLTIDNG VFEVVATNGD THLGGEDFDQ RVMEHFIKLY KKKTGKDVRK DNRAVQKLRR EVEKAKRALS SQHQARIEIE SFYEGEDFSE TLTRAKFEEL NMDLFRSTMK PVQKVLEDSD LKKSDIDEIV LVGGSTRIPK IQQLVKEFFN GKEPSRGINP DEAVAYGAAV QAGVLSGDQD TGDLVLLDVC PLTLGIETVG GVMTKLIPRN TVVPTKKSQI FSTASDNQPT VTIKVYEGER PLTKDNHLLG TFDLTGIPPA PRGVPQIEVT FEIDVNGILR VTAEDKGTGN KNKITITNDQ NRLTPEEIER MVNDAEKFAE EDKKLKERID TRNELESYAY SLKNQIGDKE KLGGKLSSED KETMEKAVEE KIEWLESHQD ADIEDFKAKK KELEEIVQPI ISKLYGSAGP PPTGEEDTAE KDELPredicted molecular weight
78 kDaTags
His tag N-TerminusAdditional sequence information
his-tagged(Gene ID 3309)(NM_005347)
Associated products
Related Products
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-GRP78 BiP antibody (ab21685)
- Anti-GRP78 BiP antibody (ab32618)
- Anti-6X His tag® antibody [4D11] (ab5000)
Specifications
Our Abpromise guarantee covers the use ofab78432in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Applications
Other
Western blot
ELISA
Functional Studies
competitive binding assays
SDS-PAGE
Form
Liquid
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
pH: 7.40Constituents: 0.61% Tris, 0.87% Sodium chloride, 10% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
Alternative names
- 78 kDa glucose regulated protein
- 78 kDa glucose-regulated protein
- AL022860
see allFunction
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.Involvement in disease
Autoantigen in rheumatoid arthritis.Sequence similarities
Belongs to the heat shock protein 70 family.Cellular localization
Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.- Information by UniProt
品牌介绍
Abcam超过1800种高质量的纯化二抗已在多种应用中得到验证，如蛋白质印迹，免疫组织化学，免疫细胞化学，ELISA和流式细胞仪。了解Abcam如何支持您的研究。
