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当前位置: 首页 > 产品中心 > juhewu > Abcam/Recombinant Human ACE2 protein (Fc Chimera) (ab273687)/1/Fc Chimera) (ab273687
商品详细Abcam/Recombinant Human ACE2 protein (Fc Chimera) (ab273687)/1/Fc Chimera) (ab273687
Abcam/Recombinant Human ACE2 protein (Fc Chimera) (ab273687)/1/Fc Chimera) (ab273687
Abcam/Recombinant Human ACE2 protein (Fc Chimera) (ab273687)/1/Fc Chimera) (ab273687
商品编号: FcChimera)(ab273687
品牌: Abcam
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Description

  • Product name

    Recombinant Human ACE2 protein (Fc Chimera)See all ACE2 proteins and peptides
  • Purity

    >95% Affinity purified.
  • Endotoxin level

    <>
  • Expression system

    HEK 293 cells
  • Accession

    Q9BYF1
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      QSTIEEQAKT FLDKFNHEAE DLFYQSSLAS WNYNTNITEE NVQNMNNAGD KWSAFLKEQS TLAQMYPLQE IQNLTVKLQL QALQQNGSSV LSEDKSKRLN TILNTMSTIY STGKVCNPDN PQECLLLEPG LNEIMANSLD YNERLWAWES WRSEVGKQLR PLYEEYVVLK NEMARANHYE DYGDYWRGDY EVNGVDGYDY SRGQLIEDVE HTFEEIKPLY EHLHAYVRAK LMNAYPSYIS PIGCLPAHLL GDMWGRFWTN LYSLTVPFGQ KPNIDVTDAM VDQAWDAQRI FKEAEKFFVS VGLPNMTQGF WENSMLTDPG NVQKAVCHPT AWDLGKGDFR ILMCTKVTMD DFLTAHHEMG HIQYDMAYAA QPFLLRNGAN EGFHEAVGEI MSLSAATPKH LKSIGLLSPD FQEDNETEIN FLLKQALTIV GTLPFTYMLE KWRWMVFKGE IPKDQWMKKW WEMKREIVGV VEPVPHDETY CDPASLFHVS NDYSFIRYYT RTLYQFQFQE ALCQAAKHEG PLHKCDISNS TEAGQKLFNM LRLGKSEPWT LALENVVGAK NMNVRPLLNY FEPLFTWLKD QNKNSFVGWS TDWSPYADGG GGSGGGGSDK THTCPPCPAP EAAGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK
    • Predicted molecular weight

      190 kDa including tags
    • Amino acids

      18 to 615
    • Tags

      Fc tag C-Terminus
    • Additional sequence information

      Fc domain: Human IgG1 containing silencing LALA mutations.

Associated products

  • Related Products

    • Recombinant Human ACE2 (mutated H374N + H378N) protein (Fc Chimera) (ab273885)

Specifications

Our Abpromise guarantee covers the use ofab273687in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

    ELISA

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C.

    Constituent: PBS

General Info

  • Alternative names

    • ACE 2
    • ACE related carboxypeptidase
    • ACE-related carboxypeptidase
    • ACE2
    • ACE2_HUMAN
    • ACEH
    • Angiotensin converting enzyme 2
    • Angiotensin converting enzyme homolog
    • Angiotensin converting enzyme like protein
    • Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2
    • Angiotensin I converting enzyme 2
    • Angiotensin-converting enzyme homolog
    • DKFZP434A014
    • EC 3.4.17
    • metalloprotease MPROT 15
    • Metalloprotease MPROT15
    • OTTHUMP00000022963
    • Processed angiotensin-converting enzyme 2
    see all
  • Function

    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
  • Tissue specificity

    Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
  • Sequence similarities

    Belongs to the peptidase M2 family.
  • Post-translationalmodifications

    N-glycosylation on Asn-90 may limit SARS infectivity.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
品牌介绍
Abcam超过1800种高质量的纯化二抗已在多种应用中得到验证,如蛋白质印迹,免疫组织化学,免疫细胞化学,ELISA和流式细胞仪。了解Abcam如何支持您的研究。