Overview
Product name
Tetrodotoxin citrate, Na+ channel blockerDescription
Na+ channel blocker; water-solubleAlternative names
- TTX
- TTX citrate
Biological description
Water soluble citrate salt of tetrodotoxin. Potent, selective and reversible, use-dependent inhibitor of voltage-dependent Na+ channels.
Purity
>98%General notes
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CAS Number
18660-81-6Chemical structure
Properties
Chemical name
Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d] pyrimidine-4,7,10,11,12-pentol + citrate buffer
Molecular weight
511.40Molecular formula
C11H17N3O8.C6H8O7PubChem identifier
205806Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.Solubility overview
Soluble in water
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES
O=C(O)C(O)(CC(=O)O)CC(=O)O.O[C@H]3C14NC(=N)N[C@H](O)[C@@H]4C2O[C@]3(O)O[C@H](C1O)C2(O)COSource
Fugu
Research areas
- Biochemicals
- Product Range
- Just Add Water
- Biochemicals
- Chemical Type
- Biochemicals
- Biochemicals
- Chemical Type
- Toxin
- Biochemicals
- Pharmacology
- Ion Channels
- Sodium
- Blockers
- Biochemicals
- Research Area
- Diabetes
- Sodium
- Blockers
- Biochemicals
- Research Area
- Heart disease
- Sodium
- Blockers
- Biochemicals
- Research Area
- Hypertension
- Sodium
- Blockers
- Biochemicals
- Research Area
- Obesity
- Sodium
- Blockers
- Biochemicals
- Research Area
- Pain & inflammation
- Sodium
- Blockers
- Biochemicals
- Research Area
- Respiratory disease
- Sodium
- Blockers
- Biochemicals
- Research Area
- Stroke
- Sodium
- Blockers
